For Research Purposes Only. This page summarizes published preclinical and clinical research. It does not constitute medical advice and is not a recommendation for human use.
Semax
ACTH(4-7)-derived heptapeptide nootropic developed in Russia — studied for neuroprotection, attention, and BDNF-related signaling.
01 · What is Semax?
Semax is a synthetic heptapeptide based on the ACTH(4-7) fragment, with a C-terminal Pro-Gly-Pro extension that stabilizes it against enzymatic breakdown. Developed in Russia — where it is approved for clinical use — it is studied for neuroprotection, attention, and BDNF-related signaling. It is typically administered intranasally in research settings.
Sizes currently sold by tracked vendors: 100mg, 10mg, 150mg, 25mg, 300mg, 30mg, 50mg, 5mg, 60mg, 9.5mg.
02 · Price comparison
Prices last checked Oct 26, 2026| Vendor | Sizes | Price range | Best $/mg | Stock |
|---|---|---|---|---|
| SaiyanMed | 2 | $49.00 – $80.00 | $0.80 | In stock |
| Peptide Partners | 3 | $81.00 – $310.50 | $1.03 | In stock |
| HkRoids | 2 | $63.00 – $110.00 | $1.10 | In stock |
| Reta-Peptide | 1 | $95.00 | $1.90 | In stock |
| Peptide Pros | 1 | $58.25 | $1.94 | In stock |
| Biotech Peptides | 1 | $53.00 | $2.12 | In stock |
| Paramount Peptides | 1 | $68.00 | $2.27 | In stock |
| Raw AminoVerified | 1 | $58.00 | $2.32 | In stock |
| Umbrella LabsVerified | 3 | $29.99 – $69.99 | $2.33 | In stock |
| Go Alpha Labs | 4 | $21.69 – $237.99 | $2.38 | In stock |
| Swiss Chems | 2 | $73.95 – $739.50 | $2.46 | In stock |
| Core Peptides | 1 | $63.00 | $2.52 | In stock |
| Sunrise BioResearch | 3 | $26.98 – $256.31 | $2.56 | In stock |
| NextechLabs | 2 | $29.25 – $291.77 | $2.92 | In stock |
| NUPEPS | 1 | $31.00 | $3.10 | In stock |
| Verified Peptides | 1 | $96.00 | $3.20 | In stock |
| Eternal Peptides | 2 | $34.99 | $3.50 | In stock |
| Hydro Research | 1 | $35.00 | $3.50 | In stock |
| Peptides 4 Research | 1 | $35.00 | $3.50 | In stock |
| Behemoth Labz | 1 | $108.95 | $3.63 | In stock |
| Injectify | 1 | $18.99 | $3.80 | In stock |
| Royal Peptides | 2 | $65.00 – $430.00 | $4.30 | In stock |
| Peptidology | 2 | $38.00 – $42.00 | $4.42 | In stock |
| Steady Meds | 2 | $40.00 – $45.00 | $4.50 | In stock |
| Oasis Labs | 1 | $45.00 | $4.50 | In stock |
| Mei Peptide | 2 | $30.00 – $85.00 | $6.00 | In stock |
| Loti Labs | 1 | $39.99 | $8.00 | In stock |
| Alpha-Gen | 1 | $83.19 | $8.32 | In stock |
| UWA Elite Peptides | 1 | $85.00 | $8.50 | In stock |
| Nextwave Peptides | 2 | $59.00 – $89.00 | $8.90 | In stock |
30 vendors tracked · prices scraped weekly from vendor sites · open full comparison table →
03 · Third-party purity data
Full data at peptigrity.com ↗Independent HPLC test results — averages across multiple samples.
04 · Frequently asked questions
What is Semax?
Semax is a synthetic heptapeptide based on the ACTH(4-7) fragment, with a C-terminal Pro-Gly-Pro extension that stabilizes it against enzymatic breakdown. Developed in Russia — where it is approved for clinical use — it is studied for neuroprotection, attention, and BDNF-related signaling. It is typically administered intranasally in research settings.
Is Semax FDA approved?
Not in the US — it is approved for clinical use in Russia and some neighboring countries. In the US it is sold as a research chemical.
How much does Semax cost?
Across 30 vendors tracked by PepVendors, Semax currently runs $0.80–$8.90 per mg at each vendor's best price tier (30 showing in stock). Vial prices and size tiers vary — the live comparison table on this page lists current pricing.
Which vendors have third-party purity data for Semax?
Independent labs (Finnrick Analytics, Janoshik) have published HPLC purity results for 19 samples of Semax or its components: Polaris Peptides (100.0%), Nexaph (100.0%), Peptide Partners (99.9%), Oasis Labs (99.9%), Loti Labs (99.9%), NUPEPS (99.8%), Prime Peptides (99.6%), Royal Peptides (99.6%), Eternal Peptides (99.5%), Limitless Life (99.5%), SaiyanMed (99.5%), Peptidology (99.4%), Injectify (99.3%), HkRoids (99.3%), Sunrise BioResearch (99.2%), Liberty Peptides (99.2%), Paramount Peptides (99.1%), Umbrella Labs (99.1%), Biolongevity Labs (98.8%). A grade A (≥98%) is the appropriate baseline for research use — check the linked lab reports for batch-level detail and fill-accuracy data.