For Research Purposes Only. This page summarizes published preclinical and clinical research. It does not constitute medical advice and is not a recommendation for human use.
IGF-1 LR3
Long-acting recombinant IGF-1 analogue — 83 residues with modifications that extend half-life to ~20–30 hours.
01 · What is IGF-1 LR3?
IGF-1 LR3 is a recombinant analogue of insulin-like growth factor 1: the native 70-amino-acid sequence extended by a 13-residue N-terminal peptide plus an arginine substitution at position 3. These modifications reduce binding-protein affinity and extend its half-life from minutes to roughly 20–30 hours. It is studied for muscle protein synthesis and cellular growth signaling.
Sizes currently sold by tracked vendors: 0.1mg, 0.83mg, 10mg, 1MG, 1mg, 4mg.
02 · Price comparison
Prices last checked Oct 26, 2026| Vendor | Sizes | Price range | Best $/mg | Stock |
|---|---|---|---|---|
| HkRoids | 2 | $50.00 – $245.00 | $24.50 | In stock |
| SaiyanMed | 1 | $272.00 | $27.20 | In stock |
| Umbrella LabsVerified | 2 | $89.99 – $300.99 | $30.10 | In stock |
| Go Alpha Labs | 2 | $46.89 – $352.09 | $35.21 | In stock |
| NUPEPS | 1 | $45.50 | $45.50 | In stock |
| Verified Peptides | 1 | $47.50 | $47.50 | In stock |
| NextechLabs | 1 | $58.50 | $58.50 | In stock |
| Royal Peptides | 2 | $78.00 – $590.00 | $59.00 | In stock |
| Swiss Chems | 2 | $59.96 – $599.60 | $59.96 | In stock |
| Injectify | 2 | $14.99 – $65.99 | $65.99 | In stock |
| Oasis Labs | 1 | $67.00 | $67.00 | In stock |
| Biolongevity Labs | 1 | $299.99 | $75.00 | Out of stock |
| Pinnacle Peptides | 2 | $79.99 | $79.99 | In stock |
| Loti Labs | 1 | $79.99 | $79.99 | In stock |
| Accelerate Labs | 1 | $84.99 | $84.99 | In stock |
| Paramount Peptides | 1 | $85.00 | $85.00 | In stock |
| Peptides 4 Research | 1 | $85.00 | $85.00 | In stock |
| Hydro Research | 1 | $85.00 | $85.00 | In stock |
| Peptide Pros | 1 | $89.99 | $89.99 | In stock |
| Pure Tested Peptides | 1 | $99.98 | $99.98 | In stock |
| Alpha-Gen | 1 | $100.00 | $100.00 | In stock |
| Peptidology | 2 | $68.80 – $86.00 | $103.61 | In stock |
| Mei Peptide | 2 | $43.00 – $187.00 | $187.00 | In stock |
| Raw AminoVerified | 1 | $230.00 | $230.00 | Out of stock |
| PeptiSlim | 2 | $80.00 – $350.00 | $350.00 | In stock |
| Steady Meds | 1 | $35.00 | $350.00 | In stock |
26 vendors tracked · prices scraped weekly from vendor sites · open full comparison table →
03 · Third-party purity data
Full data at peptigrity.com ↗Independent HPLC test results — averages across multiple samples.
| Vendor | Purity |
|---|---|
| Eternal Peptidesreport ↗ | |
| Peptidologyreport ↗ | |
| Oasis Labsreport ↗ | 99.6%APeptigrityVendor-published only |
| Royal Peptidesreport ↗ | |
| Verified Peptidesreport ↗ | |
| Hydro Researchreport ↗ | |
| Loti Labsreport ↗ | 99.3%APeptigrityVendor-published only |
| Core Peptidesreport ↗ | |
| Go Alpha Labsreport ↗ | |
| Umbrella Labsreport ↗ | |
| Paramount Peptidesreport ↗ | 98.0%ADisclosed LabsVendor-published only |
| Simple Peptidereport ↗ | |
| HkRoidsreport ↗ | |
| Injectifyreport ↗ | 94.7%CPeptigrityVendor-published only |
04 · Frequently asked questions
What is IGF-1 LR3?
IGF-1 LR3 is a recombinant analogue of insulin-like growth factor 1: the native 70-amino-acid sequence extended by a 13-residue N-terminal peptide plus an arginine substitution at position 3. These modifications reduce binding-protein affinity and extend its half-life from minutes to roughly 20–30 hours. It is studied for muscle protein synthesis and cellular growth signaling.
Is IGF-1 LR3 FDA approved?
No. IGF-1 LR3 is not FDA-approved. (Native IGF-1 exists as an approved drug — mecasermin/Increlex for severe primary IGF-1 deficiency — but the LR3 analogue is a distinct research compound.)
How much does IGF-1 LR3 cost?
Across 26 vendors tracked by PepVendors, IGF-1 LR3 currently runs $24.50–$350.00 per mg at each vendor's best price tier (24 showing in stock). Vial prices and size tiers vary — the live comparison table on this page lists current pricing.
Which vendors have third-party purity data for IGF-1 LR3?
Independent labs (Finnrick Analytics, Janoshik) have published HPLC purity results for 14 samples of IGF-1 LR3 or its components: Eternal Peptides (99.8%), Peptidology (99.7%), Oasis Labs (99.6%), Royal Peptides (99.6%), Verified Peptides (99.5%), Hydro Research (99.5%), Loti Labs (99.3%), Core Peptides (99.0%), Go Alpha Labs (98.9%), Umbrella Labs (98.0%), Paramount Peptides (98.0%), Simple Peptide (98.0%), HkRoids (97.8%), Injectify (94.7%). A grade A (≥98%) is the appropriate baseline for research use — check the linked lab reports for batch-level detail and fill-accuracy data.